BMS, amenorrhea, sterility: oral: CLL, indolent lymphomas, Waldenstrom’s Sx … aka Dactinomycin, intercalates, causes DNA bends, may inhibit RNA pol …
1 Drug Pronunciation Target/Mechanism Significant Side effects Administration Therapeutic Uses
2 A l k y l a t I n g A g e n t s Nitrogen Mustards Mechlorethamine me-klor-ETH-a-meen bifunctional, bind to DNA bases, crosslink BMS, severe nausea/vomit, vessicant IV only Hodgkins ( M OPP) mycosis fungoides (lymphoma
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